Entrants were tasked to create their own Mixel with its own name, tribe, home, and powers.
- Slumbo and Tentro are the only Series 2 Mixels who did not appear on the page promoting the competition.
- The Canadian issues of the magazine lacked the competition. Because of this, the January/February 2015 issues of the Canadian version of the magazine had the Mixed Up Maze in its place.
Games (Calling All Mixels / Mixels Rush / Mixels Mania / Who's In The Mix / Mix Your Neighbor / Infernites Game / Cragsters Game / Electroids Game / Frosticons Game / Fang Gang Game / Flexers Game / Glorp Corp Game / Spikels Game / Wiztastics Game)
Make a Mixel... Make a Story! Competition / Glomp's Gooey, Sneezy Cold! / Mixels in SPAAAAACE!! Puzzle / Mixed Up Maze / Mixels Convention Craze / Mixed Up Punchlines! / Make-Your-Own Mixels: The Game! / Mixopolis Music Mix-Up! / Nixels' New Adventure! / The Great Mixel Mix-Up! / The Mixopolis TimesTimeline / Mixels Story Guide